Antiphospholipid Syndrome: Report of Three Cases and Review of the Literature Síndrome Antifosfolipídica: Uma Revisão a Propósito de Três Casos Clínicos

Abstract

The antiphospholipid syndrome is an autoimmune of antiphospholipid antibodies and a systemic disease that is defined based upon clinical and laboratory findings, ie, the presence of recurrent, arterial or venous thrombosis in young people, recurrent spontaneous abortions, thrombocytopenia and elevated antibody levels: lupus anticoagulant, anticardiolipin IgG or IgM antibody, as well as IgM or IgG anti-beta 2-glycoprotein I and antiprothrombin. In individuals with antiphospholipid syndrome, the syndrome may present alone or in association with other disorders, including other autoimmune diseases such as lupus erythematosus, which are among the most commonly associated. In this article the authors present three cases in which the thrombotic manifestations of antiphospholipid syndrome led to the investigation of the diagnosis, which came to be confirmed by immunological study. The use of the right therapeutic prevented episodes of recurrence. 

Received: 31/05/2016 – Accepted: 19/07/2016